AirHint found the following cheapest return flights from Houston (HOU) to Rome (FCO) in September 2025 (see full year).

Return flights

25 Sep - 07 Oct	Spirit Airlines
09 Sep - 16 Sep	Spirit Airlines
10 Sep - 23 Sep	Spirit Airlines
08 Sep - 24 Sep	Spirit Airlines
30 Sep - 29 Oct	Spirit Airlines
17 Sep - 23 Sep	Air Canada
02 Sep - 11 Sep	Air Canada
01 Sep - 10 Sep	Air Canada
21 Sep - 14 Oct	British Airways
19 Sep - 10 Oct	Spirit Airlines
05 Sep - 11 Sep	Spirit Airlines
15 Sep - 05 Oct	Spirit Airlines
21 Sep - 09 Oct	Delta
05 Sep - 12 Sep	Spirit Airlines
15 Sep - 22 Sep	United
11 Sep - 18 Sep	United
27 Sep - 07 Oct	United
25 Sep - 26 Oct	Spirit Airlines
25 Sep - 06 Oct	Delta
27 Sep - 04 Oct	United

Also check the deals for one-way flights from Houston to Rome in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Houston to Rome in September from 417€

Return flights