AirHint found the following cheapest return flights from Houston (HOU) to Rome (FCO) in September 2025 (see full year).

Return flights

08 Sep - 24 Sep	Spirit Airlines
08 Sep - 09 Sep	Spirit Airlines
07 Sep - 19 Sep	Spirit Airlines
13 Sep - 20 Sep	Frontier Airlines
12 Sep - 17 Sep	Spirit Airlines
05 Sep - 19 Sep	Frontier Airlines
07 Sep - 09 Sep	Spirit Airlines
27 Sep - 07 Oct	Frontier Airlines
06 Sep - 20 Sep	Spirit Airlines
12 Sep - 24 Sep	Frontier Airlines
13 Sep - 21 Sep	Frontier Airlines
19 Sep - 10 Oct	Spirit Airlines
29 Sep - 06 Oct	United
15 Sep - 05 Oct	Frontier Airlines
25 Sep - 06 Oct	Delta
26 Sep - 03 Oct	United

Also check the deals for one-way flights from Houston to Rome in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Houston to Rome in September from 411€

Return flights