AirHint found the following cheapest return flights from Heraklion (HER) to Istanbul (IST) in May 2026 (see full year).

Return flights

22 May - 26 May	SKY express
19 May - 23 May	Aegean Airlines
09 May - 12 May	Aegean Airlines
02 May - 05 May	Aegean Airlines	direct
21 May - 24 May	Aegean Airlines
23 May - 26 May	Aegean Airlines
24 May - 06 Jun	SKY express
24 May - 10 Jun	SKY express
03 May - 09 May	SKY express
29 May - 01 Jun	Aegean Airlines
03 May - 23 May	SKY express
03 May - 21 May	SKY express

Also check the deals for one-way flights from Heraklion to Istanbul in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Heraklion to Istanbul in May from 145€

Return flights