AirHint found the following cheapest return flights from Guayaquil (GYE) to Rio Negro (MDE) in December 2025 (see full year).

Return flights

02 Dec - 05 Dec	Avianca
22 Dec - 26 Dec	Avianca	direct
08 Dec - 12 Dec	Avianca	direct
12 Dec - 15 Dec	Avianca
24 Dec - 02 Jan	Avianca
05 Dec - 08 Dec	Avianca
10 Dec - 15 Dec	Avianca
10 Dec - 14 Dec	Avianca
23 Dec - 05 Jan	Avianca
11 Dec - 14 Dec	Avianca
15 Dec - 23 Dec	Avianca
02 Dec - 08 Dec	Avianca
26 Dec - 02 Jan	Avianca
21 Dec - 03 Jan	Avianca
29 Dec - 02 Jan	Avianca

Also check the deals for one-way flights from Guayaquil to Rio Negro in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Guayaquil to Rio Negro in December from 247€

Return flights