AirHint found the following cheapest return flights from Guayaquil (GYE) to Madrid (MAD) in October 2025 (see full year).

Return flights

29 Oct - 12 Nov	Air Europa	direct
22 Oct - 21 Nov	LATAM Airlines Group
22 Oct - 21 Nov	Air Europa	direct
12 Oct - 02 Nov	Avianca
22 Oct - 24 Oct	Air Europa	direct
24 Oct - 04 Nov	Avianca
23 Oct - 05 Nov	Avianca
15 Oct - 11 Nov	Avianca
30 Oct - 28 Nov	Avianca
17 Oct - 28 Nov	Avianca
27 Oct - 09 Nov	Avianca
24 Oct - 27 Oct	Avianca
17 Oct - 29 Oct	Avianca
24 Oct - 31 Oct	Avianca
10 Oct - 30 Oct	Avianca
15 Oct - 22 Oct	Avianca
12 Oct - 22 Oct	Avianca
19 Oct - 22 Oct	Avianca
14 Oct - 21 Oct	Avianca
14 Oct - 29 Oct	Avianca

Also check the deals for one-way flights from Guayaquil to Madrid in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Guayaquil to Madrid in October from 687€

Return flights