Cheapest return flights from Guatemala City to Panama City in December from 253€

AirHint found the following cheapest return flights from Guatemala City (GUA) to Panama City (PTY) in December 2025 (see full year).

Return flights

01 Dec - 05 Dec Avianca
01 Dec - 31 Dec Avianca
10 Dec - 21 Dec Avianca
10 Dec - 22 Dec Avianca
15 Dec - 26 Dec Avianca
15 Dec - 20 Dec Avianca
18 Dec - 23 Dec Avianca
12 Dec - 18 Dec Avianca
04 Dec - 07 Dec Avianca
15 Dec - 19 Dec Avianca
22 Dec - 03 Jan Copa direct
28 Dec - 03 Jan Copa direct
27 Dec - 04 Jan Copa
20 Dec - 03 Jan Copa direct
27 Dec - 04 Jan Copa direct

Also check the deals for one-way flights from Guatemala City to Panama City in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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