AirHint found the following cheapest return flights from Guatemala City (GUA) to Panama City (PTY) in November 2025 (see full year).

Return flights

14 Nov - 23 Nov	Avianca
25 Nov - 28 Nov	Avianca
11 Nov - 13 Nov	Avianca
25 Nov - 29 Nov	Avianca
29 Nov - 01 Dec	Avianca
02 Nov - 06 Nov	Copa
03 Nov - 06 Nov	Copa	direct
07 Nov - 15 Nov	Copa	direct
24 Nov - 28 Nov	Copa
15 Nov - 29 Nov	Copa	direct
11 Nov - 13 Nov	Copa	direct
29 Nov - 01 Dec	Copa	direct
28 Nov - 01 Dec	Copa
30 Nov - 02 Dec	Copa
28 Nov - 07 Dec	Copa

Also check the deals for one-way flights from Guatemala City to Panama City in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Guatemala City to Panama City in November from 169€

Return flights