AirHint found the following cheapest return flights from Guatemala City (GUA) to Panama City (PTY) in November 2025 (see full year).

Return flights

20 Nov - 25 Nov	Avianca
08 Nov - 10 Nov	Avianca
07 Nov - 15 Nov	Avianca
11 Nov - 15 Nov	Avianca
04 Nov - 09 Nov	Avianca
11 Nov - 16 Nov	Avianca
03 Nov - 06 Nov	Avianca
21 Nov - 17 Dec	Avianca
19 Nov - 23 Nov	Avianca
13 Nov - 19 Nov	Avianca
11 Nov - 19 Nov	Avianca
25 Nov - 09 Dec	Avianca
29 Nov - 05 Dec	Avianca
29 Nov - 02 Dec	Avianca
28 Nov - 02 Dec	Avianca
28 Nov - 06 Dec	Avianca
26 Nov - 02 Dec	Avianca
30 Nov - 03 Dec	Copa
29 Nov - 05 Dec	Copa	direct
28 Nov - 06 Dec	Copa	direct

Also check the deals for one-way flights from Guatemala City to Panama City in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Guatemala City to Panama City in November from 153€

Return flights