AirHint found the following cheapest return flights from Sao Paulo (GRU) to Panama City (PTY) in November 2025 (see full year).

Return flights

28 Nov - 05 Dec	Avianca
24 Nov - 07 Dec	Avianca
24 Nov - 08 Dec	Avianca
20 Nov - 24 Nov	Avianca
16 Nov - 25 Nov	Avianca
02 Nov - 15 Nov	Avianca
20 Nov - 23 Nov	Avianca
16 Nov - 30 Nov	Avianca
28 Nov - 07 Dec	Avianca
28 Nov - 03 Dec	Avianca
24 Nov - 07 Dec	Copa	direct
24 Nov - 08 Dec	Copa	direct
06 Nov - 27 Nov	Copa	direct
20 Nov - 24 Nov	Copa	direct
16 Nov - 25 Nov	Copa	direct
02 Nov - 15 Nov	Copa	direct
20 Nov - 23 Nov	Copa	direct
28 Nov - 05 Dec	Copa	direct
28 Nov - 03 Dec	Copa	direct
28 Nov - 07 Dec	Copa	direct

Also check the deals for one-way flights from Sao Paulo to Panama City in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Sao Paulo to Panama City in November from 388€

Return flights