AirHint found the following cheapest return flights from Sao Paulo (GRU) to Panama City (PTY) in October 2025 (see full year).

Return flights

23 Oct - 30 Oct	Avianca
09 Oct - 14 Oct	Avianca
08 Oct - 13 Oct	Avianca
15 Oct - 20 Oct	Avianca
24 Oct - 29 Oct	Avianca
31 Oct - 30 Nov	Avianca
25 Oct - 09 Nov	Avianca
01 Oct - 06 Oct	Avianca
08 Oct - 11 Oct	Avianca
06 Oct - 14 Oct	Avianca
01 Oct - 08 Oct	Avianca
22 Oct - 29 Oct	Avianca
22 Oct - 05 Nov	Avianca
22 Oct - 06 Nov	Avianca
22 Oct - 07 Nov	Avianca
22 Oct - 08 Nov	Avianca
23 Oct - 05 Nov	Avianca
23 Oct - 06 Nov	Avianca
23 Oct - 07 Nov	Avianca
23 Oct - 08 Nov	Avianca

Also check the deals for one-way flights from Sao Paulo to Panama City in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Sao Paulo to Panama City in October from 389€

Return flights