AirHint found the following cheapest return flights from Sao Paulo (GRU) to Rio Negro (MDE) in December 2025 (see full year).

Return flights

07 Dec - 11 Dec	Avianca
02 Dec - 13 Jan	Avianca
05 Dec - 18 Jan	Avianca
27 Dec - 08 Jan	Avianca
28 Dec - 04 Jan	Avianca
25 Dec - 03 Jan	Avianca
26 Dec - 03 Jan	Avianca
29 Dec - 06 Jan	Avianca
24 Dec - 04 Jan	Avianca
23 Dec - 03 Jan	Avianca
24 Dec - 03 Jan	Avianca
22 Dec - 22 Dec	GOL Linhas Aéreas

Also check the deals for one-way flights from Sao Paulo to Rio Negro in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Sao Paulo to Rio Negro in December from 326€

Return flights