AirHint found the following cheapest return flights from Sao Paulo (GRU) to Rio Negro (MDE) in December 2025 (see full year).

Return flights

03 Dec - 23 Dec	Copa
05 Dec - 14 Dec	Arajet
08 Dec - 14 Dec	Arajet
02 Dec - 12 Dec	Arajet
02 Dec - 09 Dec	Arajet
05 Dec - 07 Dec	Arajet
07 Dec - 15 Dec	GOL Linhas Aéreas
08 Dec - 15 Dec	GOL Linhas Aéreas
08 Dec - 16 Dec	GOL Linhas Aéreas
05 Dec - 19 Dec	Arajet
26 Dec - 02 Jan	LATAM Airlines Group
05 Dec - 13 Jan	Arajet
29 Dec - 01 Jan	Sky Airline
31 Dec - 16 Jan	GOL Linhas Aéreas
31 Dec - 09 Jan	LATAM Airlines Group
13 Dec - 17 Jan	LATAM Airlines Group
21 Dec - 01 Jan	Azul Airlines
12 Dec - 10 Jan	LATAM Airlines Group
28 Dec - 02 Jan	LATAM Airlines Group
04 Dec - 14 Jan	Copa

Also check the deals for one-way flights from Sao Paulo to Rio Negro in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Sao Paulo to Rio Negro in December from 398€

Return flights