AirHint found the following cheapest return flights from Sao Paulo (GRU) to Istanbul (IST) in September 2025 (see full year).

Return flights

27 Sep - 06 Oct	British Airways
15 Sep - 24 Sep	GOL Linhas Aéreas
16 Sep - 08 Oct	Ethiopian Airlines
24 Sep - 01 Oct	Avianca
30 Sep - 13 Oct	Air France
22 Sep - 06 Oct	Ethiopian Airlines
22 Sep - 29 Sep	Avianca
21 Sep - 27 Sep	Avianca
17 Sep - 24 Sep	Ethiopian Airlines
18 Sep - 25 Sep	KLM
19 Sep - 01 Oct	Avianca
23 Sep - 01 Oct	Air France
30 Sep - 07 Oct	ITA Airways
29 Sep - 08 Oct	Air France
30 Sep - 22 Oct	ITA Airways
20 Sep - 29 Sep	Avianca
14 Sep - 21 Sep	GOL Linhas Aéreas
24 Sep - 30 Sep	Ethiopian Airlines
14 Sep - 23 Sep	KLM
23 Sep - 30 Sep	Ethiopian Airlines

Also check the deals for one-way flights from Sao Paulo to Istanbul in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Sao Paulo to Istanbul in September from 747€

Return flights