AirHint found the following cheapest return flights from Sao Paulo (GRU) to Istanbul (IST) in April 2026 (see full year).

Return flights

28 Apr - 09 May	TAP
25 Apr - 05 May	Air Europa
26 Apr - 06 May	Air Europa
21 Apr - 05 May	Air Europa
27 Apr - 12 May	Air Europa
21 Apr - 29 Apr	ITA Airways
25 Apr - 06 May	Air Europa
27 Apr - 13 May	Air Europa
24 Apr - 07 May	Air Europa
22 Apr - 05 May	Air Europa
30 Apr - 18 May	British Airways
07 Apr - 21 Apr	Air Europa
02 Apr - 05 Apr	Air Europa
13 Apr - 22 Apr	Air Europa
05 Apr - 10 Apr	Air Europa
08 Apr - 15 Apr	Air Europa
08 Apr - 19 Apr	Air Europa
04 Apr - 13 Apr	Air Europa
01 Apr - 11 Apr	Air Europa
08 Apr - 20 Apr	Air Europa

Also check the deals for one-way flights from Sao Paulo to Istanbul in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Istanbul

Cheap car rent in Istanbul

Cheapest return flights from Sao Paulo to Istanbul in April from 776€

Return flights