AirHint found the following cheapest return flights from Sao Paulo (GRU) to Istanbul (IST) in December 2025 (see full year).

Return flights

01 Dec - 08 Dec	British Airways
09 Dec - 28 Dec	Air Europa
12 Dec - 28 Dec	Air Europa
12 Dec - 27 Dec	Air Europa
12 Dec - 26 Dec	Air Europa
14 Dec - 28 Dec	Air Europa
13 Dec - 27 Dec	Air Europa
10 Dec - 23 Dec	Air France
30 Dec - 10 Jan	ITA Airways
09 Dec - 28 Dec	Turkish Airlines	direct
12 Dec - 26 Dec	Turkish Airlines	direct
13 Dec - 03 Jan	Turkish Airlines	direct
26 Dec - 02 Jan	Turkish Airlines	direct
26 Dec - 08 Jan	Turkish Airlines	direct
23 Dec - 04 Jan	Turkish Airlines	direct
30 Dec - 10 Jan	Turkish Airlines	direct
26 Dec - 03 Jan	KLM

Also check the deals for one-way flights from Sao Paulo to Istanbul in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Sao Paulo to Istanbul in December from 731€

Return flights