AirHint found the following cheapest return flights from Sao Paulo (GRU) to Istanbul (IST) in December 2025 (see full year).

Return flights

02 Dec - 29 Dec	British Airways
01 Dec - 08 Jan	Air France
31 Dec - 17 Jan	Air Europa
29 Dec - 17 Jan	Air France
28 Dec - 17 Jan	ITA Airways
29 Dec - 26 Jan	British Airways
31 Dec - 20 Jan	British Airways
21 Dec - 28 Dec	Air Europa
28 Dec - 25 Jan	British Airways
20 Dec - 11 Jan	ITA Airways
02 Dec - 29 Dec	Turkish Airlines	direct
20 Dec - 11 Jan	Turkish Airlines	direct
27 Dec - 04 Jan	Turkish Airlines	direct
21 Dec - 28 Dec	Turkish Airlines	direct

Also check the deals for one-way flights from Sao Paulo to Istanbul in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Sao Paulo to Istanbul in December from 718€

Return flights