AirHint found the following cheapest return flights from Sao Paulo (GRU) to Istanbul (IST) in December 2025 (see full year).

Return flights

23 Dec - 11 Jan	KLM
23 Dec - 29 Dec	KLM
23 Dec - 10 Jan	KLM
26 Dec - 11 Jan	KLM
28 Dec - 13 Jan	KLM
23 Dec - 30 Dec	KLM
25 Dec - 31 Dec	KLM
29 Dec - 08 Jan	KLM
24 Dec - 11 Jan	KLM
29 Dec - 17 Jan	KLM
23 Dec - 31 Dec	KLM
24 Dec - 14 Jan	KLM
23 Dec - 30 Jan	Iberia
24 Dec - 10 Jan	KLM
22 Dec - 29 Dec	Lufthansa
24 Dec - 31 Dec	Turkish Airlines	direct
23 Dec - 30 Dec	Turkish Airlines	direct
27 Dec - 28 Dec	Ethiopian Airlines
21 Dec - 28 Dec	Turkish Airlines	direct

Also check the deals for one-way flights from Sao Paulo to Istanbul in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Sao Paulo to Istanbul in December from 953€

Return flights