AirHint found the following cheapest return flights from Sao Paulo (GRU) to Istanbul (IST) in December 2025 (see full year).

Return flights

03 Dec - 11 Dec	British Airways
09 Dec - 20 Jan	British Airways
03 Dec - 24 Dec	British Airways
10 Dec - 24 Dec	British Airways
08 Dec - 20 Jan	British Airways
11 Dec - 19 Jan	Air France
08 Dec - 31 Dec	Air Europa
06 Dec - 31 Dec	Air Europa
09 Dec - 28 Dec	ITA Airways
03 Dec - 10 Dec	ITA Airways
01 Dec - 10 Dec	British Airways
02 Dec - 10 Dec	British Airways
09 Dec - 31 Dec	ITA Airways
10 Dec - 23 Jan	ITA Airways
01 Dec - 08 Jan	Air China
16 Dec - 16 Jan	ITA Airways
14 Dec - 10 Jan	Azul Airlines
10 Dec - 10 Jan	ITA Airways
13 Dec - 14 Jan	LATAM Airlines Group
01 Dec - 02 Jan	Air China

Also check the deals for one-way flights from Sao Paulo to Istanbul in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Sao Paulo to Istanbul in December from 725€

Return flights