AirHint found the following cheapest return flights from Sao Paulo (GRU) to Istanbul (IST) in October 2025 (see full year).

Return flights

28 Oct - 11 Nov	KLM
23 Oct - 09 Nov	KLM
21 Oct - 22 Nov	Air France
25 Oct - 13 Nov	GOL Linhas Aéreas
29 Oct - 08 Nov	Air Europa
26 Oct - 08 Nov	Air France
13 Oct - 07 Nov	Air France
25 Oct - 24 Nov	Air France
27 Oct - 06 Nov	Air France
31 Oct - 09 Nov	Air Europa
24 Oct - 31 Oct	Air Europa
26 Oct - 31 Oct	Air Europa
25 Oct - 31 Oct	Air Europa
19 Oct - 28 Oct	Air Europa
21 Oct - 31 Oct	Air Europa
12 Oct - 28 Oct	Air Europa
19 Oct - 26 Oct	Air Europa
22 Oct - 29 Oct	KLM
19 Oct - 29 Oct	KLM
20 Oct - 30 Oct	Air France

Also check the deals for one-way flights from Sao Paulo to Istanbul in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Sao Paulo to Istanbul in October from 708€

Return flights