AirHint found the following cheapest return flights from Sao Paulo (GRU) to Istanbul (IST) in October 2025 (see full year).

Return flights

29 Oct - 16 Nov	British Airways
11 Oct - 12 Nov	British Airways
23 Oct - 22 Nov	British Airways
14 Oct - 10 Nov	British Airways
27 Oct - 06 Nov	British Airways
21 Oct - 01 Nov	Air Europa
26 Oct - 03 Nov	Air France
14 Oct - 21 Oct	KLM
22 Oct - 02 Nov	KLM
16 Oct - 26 Oct	ITA Airways
08 Oct - 22 Oct	Air France
05 Oct - 22 Oct	KLM
07 Oct - 20 Oct	Air France
03 Oct - 14 Oct	Air France
20 Oct - 02 Nov	KLM
02 Oct - 09 Oct	KLM
02 Oct - 16 Oct	KLM
21 Oct - 29 Oct	Air Europa
01 Oct - 07 Oct	KLM
01 Oct - 01 Nov	KLM

Also check the deals for one-way flights from Sao Paulo to Istanbul in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Sao Paulo to Istanbul in October from 720€

Return flights