AirHint found the following cheapest return flights from Rome (FCO) to Santiago (SCL) in September 2025 (see full year).

Return flights

16 Sep - 29 Sep	Delta
16 Sep - 28 Sep	Delta
06 Sep - 14 Sep	Delta
10 Sep - 03 Oct	Delta
01 Sep - 14 Sep	Delta
16 Sep - 31 Oct	Delta
08 Sep - 14 Sep	Delta
14 Sep - 21 Sep	Delta
12 Sep - 27 Sep	Delta
10 Sep - 02 Oct	Delta
18 Sep - 25 Sep	Delta
04 Sep - 24 Sep	Delta
02 Sep - 24 Sep	Delta
15 Sep - 08 Oct	Delta
14 Sep - 08 Oct	Delta
15 Sep - 09 Oct	Delta
22 Sep - 04 Oct	Delta
20 Sep - 03 Oct	Delta
20 Sep - 04 Oct	Delta
21 Sep - 03 Oct	Delta

Also check the deals for one-way flights from Rome to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rome to Santiago in September from 715€

Return flights