AirHint found the following cheapest return flights from Rome (FCO) to Santiago (SCL) in December 2025 (see full year).

Return flights

03 Dec - 09 Dec	Delta
28 Dec - 25 Jan	Delta
09 Dec - 13 Jan	Delta
05 Dec - 22 Dec	Delta
27 Dec - 25 Jan	Delta
25 Dec - 13 Jan	Delta
28 Dec - 16 Jan	Delta
26 Dec - 13 Jan	Delta
26 Dec - 14 Jan	Delta
27 Dec - 16 Jan	Delta
13 Dec - 13 Jan	Norse Atlantic Airways
05 Dec - 13 Jan	TAP
23 Dec - 30 Dec	Delta
09 Dec - 31 Dec	Wizz Air Malta
01 Dec - 01 Dec	Wizz Air Malta
11 Dec - 20 Dec	Norse Atlantic Airways
24 Dec - 31 Dec	Turkish Airlines
06 Dec - 20 Dec	Norse Atlantic Airways
19 Dec - 26 Dec	Ryanair

Also check the deals for one-way flights from Rome to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rome to Santiago in December from 767€

Return flights