AirHint found the following cheapest return flights from Rome (FCO) to Santiago (SCL) in December 2025 (see full year).

Return flights

01 Dec - 10 Dec	Air Canada
01 Dec - 11 Dec	Iberia
06 Dec - 20 Dec	Iberia
17 Dec - 30 Dec	Iberia
23 Dec - 06 Jan	Air Canada
02 Dec - 14 Jan	Delta
10 Dec - 11 Jan	Delta
27 Dec - 11 Jan	Iberia
26 Dec - 09 Jan	Iberia
25 Dec - 08 Jan	Delta
26 Dec - 08 Jan	Iberia
20 Dec - 27 Dec	Iberia
19 Dec - 13 Jan	Iberia
19 Dec - 14 Jan	Iberia
22 Dec - 05 Jan	Air Canada

Also check the deals for one-way flights from Rome to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rome to Santiago in December from 678€

Return flights