AirHint found the following cheapest return flights from Rome (FCO) to Santiago (SCL) in December 2025 (see full year).

Return flights

07 Dec - 14 Dec	Delta
02 Dec - 16 Dec	LATAM Airlines Group
11 Dec - 21 Jan	LATAM Airlines Group
28 Dec - 09 Jan	Iberia For Level
27 Dec - 11 Jan	Delta
25 Dec - 08 Jan	Iberia
18 Dec - 15 Jan	Iberia For Level
06 Dec - 10 Jan	Iberia
26 Dec - 10 Jan	Iberia For Level
26 Dec - 06 Jan	Iberia For Level
24 Dec - 05 Jan	Iberia
25 Dec - 05 Jan	Iberia
17 Dec - 24 Dec	Iberia

Also check the deals for one-way flights from Rome to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rome to Santiago in December from 965€

Return flights