AirHint found the following cheapest return flights from Rome (FCO) to Sao Paulo (GRU) in September 2025 (see full year).

Return flights

11 Sep - 15 Oct	Air France
11 Sep - 22 Oct	ITA Airways
11 Sep - 22 Oct	ITA Airways	direct
01 Sep - 25 Sep	ITA Airways	direct
10 Sep - 24 Sep	LATAM Airlines Group
10 Sep - 28 Sep	LATAM Airlines Group
18 Sep - 07 Oct	Air France
10 Sep - 28 Sep	ITA Airways	direct
11 Sep - 19 Sep	Delta
01 Sep - 15 Sep	Delta
03 Sep - 17 Sep	Delta
05 Sep - 19 Sep	Delta
06 Sep - 20 Sep	Delta
09 Sep - 23 Sep	Delta
17 Sep - 01 Oct	Delta
19 Sep - 03 Oct	Delta
22 Sep - 06 Oct	Delta
18 Sep - 03 Oct	Delta
18 Sep - 04 Oct	Delta
25 Sep - 15 Oct	Delta

Also check the deals for one-way flights from Rome to Sao Paulo in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rome to Sao Paulo in September from 581€

Return flights