AirHint found the following cheapest return flights from Rome (FCO) to Sao Paulo (GRU) in December 2025 (see full year).

Return flights

02 Dec - 10 Dec	LATAM Airlines Group	direct
04 Dec - 09 Dec	LATAM Airlines Group	direct
04 Dec - 10 Dec	LATAM Airlines Group	direct
03 Dec - 09 Dec	ITA Airways
01 Dec - 08 Dec	ITA Airways
04 Dec - 14 Dec	Lufthansa
08 Dec - 29 Jan	Iberia
03 Dec - 29 Jan	Iberia
03 Dec - 09 Dec	LATAM Airlines Group	direct
07 Dec - 30 Jan	Iberia
02 Dec - 24 Jan	Air Canada
01 Dec - 16 Dec	Air Europa
05 Dec - 08 Dec	Air Europa
25 Dec - 31 Jan	Delta
24 Dec - 26 Jan	Delta
10 Dec - 22 Jan	Delta
10 Dec - 25 Jan	Delta
05 Dec - 13 Dec	LATAM Airlines Group	direct
31 Dec - 24 Jan	Delta
26 Dec - 20 Jan	Delta

Also check the deals for one-way flights from Rome to Sao Paulo in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rome to Sao Paulo in December from 567€

Return flights