AirHint found the following cheapest return flights from Denver (DEN) to Rome (FCO) in September 2025 (see full year).

Return flights

09 Sep - 16 Sep	Air France
07 Sep - 11 Sep	Frontier Airlines
15 Sep - 15 Oct	Aer Lingus
21 Sep - 25 Sep	Frontier Airlines
03 Sep - 11 Sep	Frontier Airlines
17 Sep - 24 Sep	Frontier Airlines
04 Sep - 13 Sep	Frontier Airlines
04 Sep - 09 Sep	Turkish Airlines
28 Sep - 31 Oct	Turkish Airlines
03 Sep - 09 Sep	Frontier Airlines
12 Sep - 19 Sep	Turkish Airlines
23 Sep - 27 Sep	Frontier Airlines
17 Sep - 01 Oct	Aer Lingus
30 Sep - 07 Oct	United
29 Sep - 06 Oct	Aer Lingus
29 Sep - 31 Oct	British Airways
27 Sep - 04 Oct	United

Also check the deals for one-way flights from Denver to Rome in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Denver to Rome in September from 489€

Return flights