AirHint found the following cheapest return flights from Denver (DEN) to Rome (FCO) in October 2025 (see full year).

Return flights

27 Oct - 10 Nov	Frontier Airlines
13 Oct - 20 Oct	Frontier Airlines
10 Oct - 24 Oct	Frontier Airlines
16 Oct - 30 Oct	Frontier Airlines
01 Oct - 08 Oct	Lufthansa
07 Oct - 14 Oct	Icelandair
03 Oct - 01 Nov	Frontier Airlines
07 Oct - 21 Oct	Frontier Airlines
24 Oct - 07 Nov	Icelandair
16 Oct - 22 Oct	Frontier Airlines
04 Oct - 18 Oct	Frontier Airlines
03 Oct - 19 Oct	Icelandair
02 Oct - 16 Oct	Turkish Airlines
29 Oct - 05 Nov	United

Also check the deals for one-way flights from Denver to Rome in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Denver to Rome in October from 454€

Return flights