AirHint found the following cheapest return flights from Denver (DEN) to Rome (FCO) in October 2025 (see full year).

Return flights

02 Oct - 16 Oct	Icelandair
02 Oct - 09 Oct	Icelandair
07 Oct - 14 Oct	Icelandair
01 Oct - 08 Oct	Frontier Airlines
01 Oct - 07 Oct	Frontier Airlines
29 Oct - 12 Nov	Delta
28 Oct - 06 Nov	Air Canada
29 Oct - 05 Nov	United
14 Oct - 21 Oct	United
29 Oct - 06 Nov	Delta
10 Oct - 19 Oct	Frontier Airlines
04 Oct - 11 Oct	Frontier Airlines
09 Oct - 19 Oct	Frontier Airlines
10 Oct - 18 Oct	Condor

Also check the deals for one-way flights from Denver to Rome in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Denver to Rome in October from 485€

Return flights