AirHint found the following cheapest return flights from Cancun (CUN) to Santiago (SCL) in December 2025 (see full year).

Return flights

04 Dec - 12 Dec	Sky Airline
13 Dec - 16 Dec	Sky Airline
18 Dec - 29 Jan	LATAM Airlines Group
26 Dec - 10 Jan	LATAM Airlines Group
20 Dec - 12 Jan	Sky Airline
09 Dec - 30 Dec	Arajet
11 Dec - 06 Jan	Arajet
28 Dec - 03 Jan	Arajet
18 Dec - 07 Jan	Arajet
18 Dec - 09 Jan	Arajet
16 Dec - 31 Dec	LATAM Airlines Group
21 Dec - 26 Dec	Arajet
19 Dec - 29 Dec	LATAM Airlines Group
21 Dec - 04 Jan	Avianca

Also check the deals for one-way flights from Cancun to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cancun to Santiago in December from 401€

Return flights