AirHint found the following cheapest return flights from Cali (CLO) to Madrid (MAD) in December 2025 (see full year).

Return flights

03 Dec - 31 Jan	Avianca
04 Dec - 31 Jan	Avianca
03 Dec - 29 Jan	Avianca
04 Dec - 22 Jan	Avianca
04 Dec - 30 Jan	Avianca
10 Dec - 06 Jan	WORLD2FLY	direct
11 Dec - 30 Jan	Avianca
10 Dec - 31 Jan	Spirit Airlines
14 Dec - 27 Jan	Avianca
25 Dec - 18 Jan	Avianca
09 Dec - 30 Dec	Spirit Airlines
02 Dec - 09 Dec	JetSmart
01 Dec - 08 Dec	Copa
03 Dec - 07 Dec	Avianca
01 Dec - 07 Dec	Avianca
02 Dec - 10 Dec	Copa
04 Dec - 14 Dec	Spirit Airlines
13 Dec - 30 Dec	Avianca
06 Dec - 13 Dec	Wingo
23 Dec - 30 Dec	Avianca

Also check the deals for one-way flights from Cali to Madrid in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cali to Madrid in December from 639€

Return flights