AirHint found the following cheapest return flights from Cali (CLO) to Madrid (MAD) in December 2025 (see full year).

Return flights

02 Dec - 31 Jan	Avianca	direct
01 Dec - 30 Jan	Avianca
02 Dec - 31 Dec	Avianca
07 Dec - 07 Jan	WORLD2FLY	direct
17 Dec - 07 Jan	WORLD2FLY	direct
14 Dec - 07 Jan	WORLD2FLY	direct
16 Dec - 14 Jan	WORLD2FLY	direct
24 Dec - 11 Jan	WORLD2FLY	direct
10 Dec - 08 Jan	Avianca
12 Dec - 19 Jan	Avianca
04 Dec - 03 Jan	Avianca
19 Dec - 28 Dec	TAP
16 Dec - 23 Dec	JetSmart
02 Dec - 31 Dec	Avianca	direct
18 Dec - 27 Dec	Wingo
15 Dec - 22 Dec	TAP
20 Dec - 27 Dec	Avianca
20 Dec - 27 Dec	Avianca	direct
19 Dec - 26 Dec	Avianca

Also check the deals for one-way flights from Cali to Madrid in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cali to Madrid in December from 653€

Return flights