AirHint found the following cheapest return flights from Cali (CLO) to Madrid (MAD) in October 2025 (see full year).

Return flights

01 Oct - 19 Oct	JetSmart
08 Oct - 11 Nov	Spirit Airlines
29 Oct - 10 Nov	Spirit Airlines
28 Oct - 04 Nov	Spirit Airlines
07 Oct - 12 Nov	Spirit Airlines
14 Oct - 12 Nov	Spirit Airlines
08 Oct - 18 Oct	Avianca
08 Oct - 05 Nov	Spirit Airlines
18 Oct - 08 Nov	Spirit Airlines
22 Oct - 02 Nov	WORLD2FLY	direct
08 Oct - 08 Nov	Avianca
07 Oct - 27 Oct	Avianca
11 Oct - 23 Oct	Avianca
19 Oct - 30 Oct	Avianca
11 Oct - 28 Oct	Avianca
15 Oct - 12 Nov	JetSmart
03 Oct - 18 Oct	Spirit Airlines
24 Oct - 30 Oct	Avianca
22 Oct - 29 Oct	WORLD2FLY	direct
02 Oct - 16 Oct	Spirit Airlines

Also check the deals for one-way flights from Cali to Madrid in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cali to Madrid in October from 610€

Return flights