AirHint found the following cheapest return flights from Cali (CLO) to Madrid (MAD) in October 2025 (see full year).

Return flights

08 Oct - 22 Oct	JetSmart
12 Oct - 12 Nov	Spirit Airlines
11 Oct - 11 Nov	Spirit Airlines
11 Oct - 14 Nov	Spirit Airlines
31 Oct - 17 Nov	Avianca
30 Oct - 17 Nov	Avianca
30 Oct - 13 Nov	Avianca
28 Oct - 12 Nov	Avianca
09 Oct - 12 Nov	Avianca
14 Oct - 13 Nov	Avianca
29 Oct - 16 Nov	Avianca
11 Oct - 31 Oct	Spirit Airlines
12 Oct - 30 Oct	Spirit Airlines
12 Oct - 31 Oct	JetSmart
24 Oct - 31 Oct	Avianca
16 Oct - 31 Oct	Avianca
11 Oct - 26 Oct	Spirit Airlines
11 Oct - 18 Oct	Spirit Airlines
12 Oct - 25 Oct	LATAM Airlines Group
11 Oct - 22 Oct	Spirit Airlines

Also check the deals for one-way flights from Cali to Madrid in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cali to Madrid in October from 635€

Return flights