AirHint found the following cheapest return flights from Cali (CLO) to Antofagasta (ANF) in December 2025 (see full year).

Return flights

15 Dec - 02 Jan	JetSmart
15 Dec - 02 Jan	JetSmart	direct
23 Dec - 02 Jan	JetSmart
23 Dec - 02 Jan	JetSmart	direct
19 Dec - 02 Jan	JetSmart
19 Dec - 02 Jan	JetSmart	direct
27 Dec - 15 Jan	JetSmart	direct
01 Dec - 05 Dec	JetSmart
27 Dec - 02 Jan	JetSmart
27 Dec - 02 Jan	JetSmart	direct
01 Dec - 06 Dec	JetSmart
01 Dec - 03 Dec	JetSmart
15 Dec - 26 Dec	JetSmart
01 Dec - 06 Dec	JetSmart	direct
15 Dec - 26 Dec	JetSmart	direct
01 Dec - 13 Dec	JetSmart
01 Dec - 20 Dec	JetSmart
15 Dec - 20 Dec	JetSmart
23 Dec - 26 Dec	JetSmart

Also check the deals for one-way flights from Cali to Antofagasta in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cali to Antofagasta in December from 242€

Return flights