AirHint found the following cheapest return flights from Cali (CLO) to Antofagasta (ANF) in December 2025 (see full year).

Return flights

25 Dec - 14 Jan	JetSmart
25 Dec - 15 Jan	JetSmart
29 Dec - 19 Jan	JetSmart	direct
25 Dec - 12 Jan	JetSmart
25 Dec - 10 Jan	JetSmart
25 Dec - 10 Jan	JetSmart	direct
25 Dec - 01 Jan	JetSmart	direct
19 Dec - 01 Jan	JetSmart	direct
29 Dec - 14 Jan	JetSmart
29 Dec - 15 Jan	JetSmart
04 Dec - 11 Dec	JetSmart
25 Dec - 30 Dec	JetSmart
19 Dec - 30 Dec	JetSmart
25 Dec - 31 Dec	JetSmart
25 Dec - 27 Dec	JetSmart
19 Dec - 31 Dec	JetSmart
29 Dec - 30 Dec	JetSmart
19 Dec - 27 Dec	JetSmart
23 Dec - 30 Dec	JetSmart
25 Dec - 26 Dec	JetSmart	direct

Also check the deals for one-way flights from Cali to Antofagasta in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cali to Antofagasta in December from 287€

Return flights