AirHint found the following cheapest return flights from Cairo (CAI) to Chicago (ORD) in September 2025 (see full year).

Return flights

09 Sep - 16 Sep	LOT
10 Sep - 17 Sep	LOT
15 Sep - 22 Sep	LOT
16 Sep - 23 Sep	LOT
17 Sep - 24 Sep	LOT
22 Sep - 29 Sep	LOT
23 Sep - 30 Sep	LOT
24 Sep - 01 Oct	LOT
29 Sep - 06 Oct	LOT
30 Sep - 07 Oct	LOT
08 Sep - 15 Sep	LOT
01 Sep - 08 Sep	LOT
02 Sep - 09 Sep	LOT
22 Sep - 16 Oct	British Airways
25 Sep - 02 Oct	British Airways
26 Sep - 03 Oct	British Airways
27 Sep - 04 Oct	British Airways
28 Sep - 05 Oct	British Airways
21 Sep - 10 Oct	Delta

Also check the deals for one-way flights from Cairo to Chicago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Cairo to Chicago in September from 520€

Return flights