AirHint found the following cheapest return flights from Brussels (BRU) to Rio Negro (MDE) in December 2025 (see full year).

Return flights

29 Dec - 15 Jan	Ryanair
06 Dec - 11 Dec	Air Europa
16 Dec - 25 Jan	Ryanair
05 Dec - 11 Dec	Ryanair
27 Dec - 14 Jan	Ryanair
04 Dec - 10 Dec	Brussels Airlines
05 Dec - 07 Dec	Scandinavian Airlines
03 Dec - 10 Dec	Air Serbia
06 Dec - 08 Dec	TAP
09 Dec - 18 Dec	Vueling Airlines
14 Dec - 18 Dec	Ryanair
15 Dec - 22 Dec	Ryanair
14 Dec - 29 Dec	easyJet
30 Dec - 08 Jan	Ryanair
28 Dec - 08 Jan	Ryanair
26 Dec - 18 Jan	TUI fly Belgium
24 Dec - 09 Jan	TAP
13 Dec - 01 Jan	Ryanair
23 Dec - 07 Jan	Smart Wings
25 Dec - 01 Jan	Brussels Airlines

Also check the deals for one-way flights from Brussels to Rio Negro in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Brussels to Rio Negro in December from 939€

Return flights