AirHint found the following cheapest return flights from Boston (BOS) to Panama City (PTY) in December 2025 (see full year).

Return flights

24 Dec - 31 Dec	Frontier Airlines
26 Dec - 31 Dec	Frontier Airlines
28 Dec - 05 Jan	Arajet
21 Dec - 16 Jan	Frontier Airlines
23 Dec - 30 Dec	Frontier Airlines
21 Dec - 16 Jan	Copa	direct
25 Dec - 28 Dec	Spirit Airlines
24 Dec - 26 Dec	Frontier Airlines
25 Dec - 01 Jan	Frontier Airlines
20 Dec - 03 Jan	Copa	direct
23 Dec - 30 Dec	Copa	direct
26 Dec - 31 Dec	Copa	direct
25 Dec - 28 Dec	Copa	direct
24 Dec - 31 Dec	Copa	direct
25 Dec - 01 Jan	Copa	direct
24 Dec - 26 Dec	Copa	direct
28 Dec - 05 Jan	Copa	direct
20 Dec - 02 Jan	Copa	direct
20 Dec - 04 Jan	Copa	direct

Also check the deals for one-way flights from Boston to Panama City in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Boston to Panama City in December from 684€

Return flights