AirHint found the following cheapest return flights from Boston (BOS) to Panama City (PTY) in November 2025 (see full year).

Return flights

20 Nov - 23 Nov	Spirit Airlines
12 Nov - 03 Dec	Avianca
09 Nov - 15 Nov	Spirit Airlines
27 Nov - 01 Dec	Copa	direct
25 Nov - 01 Dec	Copa	direct
12 Nov - 03 Dec	Copa	direct
25 Nov - 29 Nov	Copa	direct
20 Nov - 23 Nov	Copa	direct
30 Nov - 07 Dec	Copa	direct
24 Nov - 30 Nov	Spirit Airlines
09 Nov - 15 Nov	Copa	direct
25 Nov - 30 Nov	Frontier Airlines
26 Nov - 30 Nov	Copa	direct
25 Nov - 30 Nov	Copa	direct
24 Nov - 30 Nov	Copa	direct
27 Nov - 04 Dec	Spirit Airlines

Also check the deals for one-way flights from Boston to Panama City in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Boston to Panama City in November from 444€

Return flights