AirHint found the following cheapest return flights from Arequipa (AQP) to Santiago (SCL) in December 2025 (see full year).

Return flights

15 Dec - 01 Jan	JetSmart
19 Dec - 01 Jan	JetSmart
11 Dec - 01 Jan	JetSmart
19 Dec - 08 Jan	JetSmart
19 Dec - 05 Jan	JetSmart
15 Dec - 05 Jan	JetSmart
29 Dec - 01 Jan	JetSmart
15 Dec - 04 Jan	JetSmart
29 Dec - 11 Jan	JetSmart
29 Dec - 08 Jan	JetSmart
15 Dec - 21 Dec	JetSmart
11 Dec - 12 Dec	JetSmart
10 Dec - 12 Dec	JetSmart
03 Dec - 12 Dec	JetSmart
08 Dec - 10 Dec	JetSmart
08 Dec - 12 Dec	JetSmart
19 Dec - 21 Dec	JetSmart
11 Dec - 21 Dec	JetSmart
02 Dec - 10 Dec	JetSmart
10 Dec - 21 Dec	JetSmart

Also check the deals for one-way flights from Arequipa to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Arequipa to Santiago in December from 247€

Return flights