AirHint found the following cheapest return flights from Amsterdam (AMS) to Panama City (PTY) in October 2025 (see full year).

Return flights

24 Oct - 21 Nov	Air Europa
09 Oct - 16 Oct	Air France
20 Oct - 17 Nov	KLM	direct
20 Oct - 26 Oct	KLM
20 Oct - 26 Oct	KLM	direct
01 Oct - 25 Oct	Delta
20 Oct - 27 Oct	Delta
16 Oct - 24 Oct	Delta
25 Oct - 01 Nov	Delta
20 Oct - 23 Oct	Delta
28 Oct - 12 Nov	Delta
22 Oct - 01 Nov	Delta
15 Oct - 06 Nov	Delta
25 Oct - 09 Nov	Delta
17 Oct - 03 Nov	Delta
20 Oct - 27 Oct	KLM	direct
09 Oct - 16 Oct	KLM	direct
15 Oct - 06 Nov	KLM	direct
01 Oct - 25 Oct	KLM	direct
25 Oct - 14 Nov	Delta

Also check the deals for one-way flights from Amsterdam to Panama City in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Amsterdam to Panama City in October from 599€

Return flights