AirHint found the following cheapest one-way flights from Santa Cruz (VVI) to Madrid (MAD) in December 2025 (see full year).
One-Way flights
| 28 Dec | Iberia | direct | |
| 31 Dec | Avianca | ||
| 27 Dec | Boliviana de Aviacion | ||
| 30 Dec | Copa | ||
| 29 Dec | Boliviana de Aviacion | ||
| 29 Dec | Iberia | direct | |
| 27 Dec | Iberia | direct | |
| 30 Dec | Boliviana de Aviacion | direct |
Also check the deals for return flights from Santa Cruz to Madrid in December.
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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.
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