Cheapest one-way flights from San Francisco to Panama City in December from 252€

AirHint found the following cheapest one-way flights from San Francisco (SFO) to Panama City (PTY) in December 2025 (see full year).

One-Way flights

09 Dec Avianca
15 Dec Frontier Airlines
14 Dec Frontier Airlines
24 Dec Aeromexico
22 Dec Hawaiian Airlines
14 Dec United direct
15 Dec United direct
09 Dec United direct
08 Dec Copa direct
01 Dec Copa direct

Also check the deals for return flights from San Francisco to Panama City in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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