Cheapest one-way flights from San Francisco to Rome in September from 281€

Best time to book flights for San Francisco (SFO) to Rome (FCO) flights at AirHint

AirHint found the following cheapest one-way flights from San Francisco (SFO) to Rome (FCO) in September 2025 (see full year).

One-Way flights

23 Sep Vueling Airlines
07 Sep Alaska Airlines
19 Sep Alaska Airlines
08 Sep Alaska Airlines
15 Sep Alaska Airlines
06 Sep Alaska Airlines
05 Sep Alaska Airlines
10 Sep Alaska Airlines
23 Sep ITA Airways direct
19 Sep ITA Airways direct

Also check the deals for return flights from San Francisco to Rome in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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