AirHint found the following cheapest one-way flights from Santo Domingo (SDQ) to Madrid (MAD) in August 2025 (see full year).

One-Way flights

06 Aug	Sky High Aviation Services
18 Aug	Arajet
09 Aug	Copa
23 Aug	Spirit Airlines
17 Aug	Copa
19 Aug	Spirit Airlines
20 Aug	Spirit Airlines
05 Aug	Frontier Airlines
12 Aug	Sky High Aviation Services
10 Aug	Sky High Aviation Services

Also check the deals for return flights from Santo Domingo to Madrid in August.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Santo Domingo to Madrid in August from 310€

One-Way flights