Cheapest one-way flights from Santo Domingo to Madrid in April from 368€

Best time to book flights for Santo Domingo (SDQ) to Madrid (MAD) flights at AirHint

AirHint found the following cheapest one-way flights from Santo Domingo (SDQ) to Madrid (MAD) in April 2025 (see full year).

One-Way flights

01 Apr Frontier Airlines
03 Apr Frontier Airlines
07 Apr Frontier Airlines
05 Apr Spirit Airlines
04 Apr Spirit Airlines
24 Apr Frontier Airlines
09 Apr Spirit Airlines
10 Apr Frontier Airlines
06 Apr Copa
28 Apr Frontier Airlines

Also check the deals for return flights from Santo Domingo to Madrid in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Madrid

Cheap car rent in Madrid