Cheapest one-way flights from Santiago to Guayaquil in December from 177€

AirHint found the following cheapest one-way flights from Santiago (SCL) to Guayaquil (GYE) in December 2025 (see full year).

One-Way flights

03 Dec LATAM Airlines Group
04 Dec LATAM Airlines Group
07 Dec LATAM Airlines Group direct
14 Dec LATAM Airlines Group
06 Dec LATAM Airlines Group
02 Dec LATAM Airlines Group
03 Dec LATAM Airlines Group direct
04 Dec LATAM Airlines Group direct
01 Dec LATAM Airlines Group
20 Dec Copa

Also check the deals for return flights from Santiago to Guayaquil in December.

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