Cheapest one-way flights from Santiago to Guayaquil in October from 164€

AirHint found the following cheapest one-way flights from Santiago (SCL) to Guayaquil (GYE) in October 2025 (see full year).

One-Way flights

22 Oct Avianca
23 Oct Avianca
14 Oct Avianca
07 Oct Avianca
05 Oct Avianca
23 Oct LATAM Airlines Group direct
15 Oct LATAM Airlines Group direct
29 Oct LATAM Airlines Group
05 Oct LATAM Airlines Group direct
14 Oct LATAM Airlines Group direct

Also check the deals for return flights from Santiago to Guayaquil in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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