Cheapest one-way flights from Santiago to Rome in September from 573€

Best time to book flights for Santiago (SCL) to Rome (FCO) flights at AirHint

AirHint found the following cheapest one-way flights from Santiago (SCL) to Rome (FCO) in September 2025 (see full year).

One-Way flights

19 Sep Iberia
17 Sep Avianca
18 Sep LATAM Airlines Group

Also check the deals for return flights from Santiago to Rome in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Rome

Cheap car rent in Rome