AirHint found the following cheapest one-way flights from Panama City (PTY) to Santiago (SCL) in December 2025 (see full year).
One-Way flights
| 01 Dec | Avianca | ||
| 24 Dec | Avianca | ||
| 27 Dec | Avianca | ||
| 29 Dec | Avianca | ||
| 27 Dec | Copa | direct | |
| 24 Dec | Copa | direct | |
| 29 Dec | Copa | direct | |
| 01 Dec | Copa | direct |
Also check the deals for return flights from Panama City to Santiago in December.
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