AirHint found the following cheapest one-way flights from Prague (PRG) to Lisbon (LIS) in December 2025 (see full year).
One-Way flights
| 02 Dec | Ryanair | ||
| 31 Dec | Ryanair | ||
| 03 Dec | Volotea | ||
| 06 Dec | Ryanair | ||
| 05 Dec | easyJet | ||
| 13 Dec | Ryanair | ||
| 11 Dec | Ryanair | ||
| 17 Dec | easyJet | ||
| 15 Dec | Ryanair | ||
| 04 Dec | easyJet | direct |
Also check the deals for return flights from Prague to Lisbon in December.
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