AirHint found the following cheapest one-way flights from Chicago (ORD) to Panama City (PTY) in May 2026 (see full year).
One-Way flights
| 23 May | Avianca | ||
| 24 May | Avianca | ||
| 22 May | Avianca | ||
| 24 May | Copa | direct | |
| 22 May | Copa | direct | |
| 23 May | Copa | direct |
Also check the deals for return flights from Chicago to Panama City in May.
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