AirHint found the following cheapest one-way flights from Chicago (ORD) to Panama City (PTY) in May 2026 (see full year).
One-Way flights
| 10 May | Frontier Airlines | ||
| 15 May | Frontier Airlines | ||
| 08 May | Frontier Airlines | ||
| 20 May | Avianca | ||
| 21 May | Avianca | ||
| 31 May | United | ||
| 11 May | Copa | direct | |
| 12 May | Copa | direct | |
| 13 May | Copa | direct | |
| 15 May | Copa | direct |
Also check the deals for return flights from Chicago to Panama City in May.
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