Cheapest one-way flights from Chicago to Sao Paulo in September from 211€

AirHint found the following cheapest one-way flights from Chicago (ORD) to Sao Paulo (GRU) in September 2025 (see full year).

One-Way flights

23 Sep Spirit Airlines
17 Sep Spirit Airlines
29 Sep Spirit Airlines
18 Sep Spirit Airlines
20 Sep Spirit Airlines
04 Sep Spirit Airlines
26 Sep Spirit Airlines
01 Sep Spirit Airlines
28 Sep Frontier Airlines
10 Sep Avianca

Also check the deals for return flights from Chicago to Sao Paulo in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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