Cheapest one-way flights from Chicago to Sao Paulo in September from 516€

Best time to book flights for Chicago (ORD) to Sao Paulo (GRU) flights at AirHint

AirHint found the following cheapest one-way flights from Chicago (ORD) to Sao Paulo (GRU) in September 2025 (see full year).

One-Way flights

15 Sep Air Canada
26 Sep Copa
26 Sep United direct
15 Sep United direct

Also check the deals for return flights from Chicago to Sao Paulo in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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