Cheapest one-way flights from Chicago to Rome in September from 192€

AirHint found the following cheapest one-way flights from Chicago (ORD) to Rome (FCO) in September 2025 (see full year).

One-Way flights

30 Sep Spirit Airlines
28 Sep Spirit Airlines
06 Sep Spirit Airlines
10 Sep Spirit Airlines
26 Sep Frontier Airlines
25 Sep Spirit Airlines
09 Sep Spirit Airlines
07 Sep Icelandair
21 Sep Spirit Airlines
29 Sep Spirit Airlines

Also check the deals for return flights from Chicago to Rome in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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