Cheapest one-way flights from Chicago to Rome in September from 164€

AirHint found the following cheapest one-way flights from Chicago (ORD) to Rome (FCO) in September 2025 (see full year).

One-Way flights

27 Sep TAP
28 Sep TAP
22 Sep TAP
07 Sep TAP
24 Sep Spirit Airlines
23 Sep Spirit Airlines
29 Sep TAP
25 Sep Spirit Airlines
20 Sep Spirit Airlines
14 Sep TAP

Also check the deals for return flights from Chicago to Rome in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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