Cheapest one-way flights from Mexico City to Santiago in April from 259€

AirHint found the following cheapest one-way flights from Mexico City (MEX) to Santiago (SCL) in April 2026 (see full year).

One-Way flights

17 Apr Avianca
01 Apr Avianca
17 Apr LATAM Airlines Group direct

Also check the deals for return flights from Mexico City to Santiago in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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