AirHint found the following cheapest one-way flights from Mendoza (MDZ) to Santiago (SCL) in October 2025 (see full year).

One-Way flights

03 Oct	JetSmart	direct
30 Oct	JetSmart	direct
25 Oct	JetSmart	direct
16 Oct	JetSmart	direct
31 Oct	JetSmart	direct
24 Oct	JetSmart	direct
11 Oct	JetSmart	direct
04 Oct	JetSmart	direct
02 Oct	JetSmart	direct
26 Oct	JetSmart	direct

Also check the deals for return flights from Mendoza to Santiago in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Mendoza to Santiago in October from 61€

One-Way flights