Cheapest one-way flights from Chicago to Istanbul in September from 264€

AirHint found the following cheapest one-way flights from Chicago (MDW) to Istanbul (IST) in September 2025 (see full year).

One-Way flights

04 Sep Frontier Airlines
23 Sep Frontier Airlines
03 Sep Frontier Airlines
11 Sep Frontier Airlines
13 Sep Frontier Airlines
20 Sep Frontier Airlines
05 Sep Frontier Airlines
25 Sep Frontier Airlines
01 Sep KLM
18 Sep Frontier Airlines

Also check the deals for return flights from Chicago to Istanbul in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Istanbul

Cheap car rent in Istanbul

Feel free to contact us with any feedback or request another flight research.