Cheapest one-way flights from Chicago to Istanbul in April from 322€

AirHint found the following cheapest one-way flights from Chicago (MDW) to Istanbul (IST) in April 2026 (see full year).

One-Way flights

26 Apr Frontier Airlines
27 Apr Frontier Airlines
25 Apr Frontier Airlines
20 Apr Frontier Airlines
19 Apr Frontier Airlines
18 Apr Frontier Airlines
24 Apr Frontier Airlines
02 Apr Frontier Airlines
08 Apr Porter Airlines (Canada) Ltd
07 Apr Frontier Airlines

Also check the deals for return flights from Chicago to Istanbul in April.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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