AirHint found the following cheapest one-way flights from Madrid (MAD) to Santa Cruz (VVI) in June 2026 (see full year).

One-Way flights

25 Jun	Avianca
27 Jun	Avianca
29 Jun	Royal Air Maroc
26 Jun	LATAM Airlines Group
19 Jun	Avianca
30 Jun	Air Europa
28 Jun	ITA Airways
19 Jun	Boliviana de Aviacion	direct
28 Jun	Iberia	direct
26 Jun	Iberia	direct

Also check the deals for return flights from Madrid to Santa Cruz in June.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Madrid to Santa Cruz in June from 390€

One-Way flights