AirHint found the following cheapest one-way flights from Madrid (MAD) to Santa Cruz (VVI) in April 2026 (see full year).
One-Way flights
| 15 Apr | Avianca | ||
| 24 Apr | Avianca | ||
| 09 Apr | Avianca | ||
| 11 Apr | Avianca | ||
| 29 Apr | Air Europa | direct | |
| 24 Apr | Boliviana de Aviacion | direct | |
| 04 Apr | LATAM Airlines Group | ||
| 11 Apr | Air Europa | direct | |
| 04 Apr | Air Europa | direct |
Also check the deals for return flights from Madrid to Santa Cruz in April.
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