Cheapest one-way flights from Madrid to Santa Cruz in November from 414€

Best time to book flights for Madrid (MAD) to Santa Cruz (VVI) flights at AirHint

AirHint found the following cheapest one-way flights from Madrid (MAD) to Santa Cruz (VVI) in November 2025 (see full year).

One-Way flights

28 Nov LATAM Airlines Group
01 Nov LATAM Airlines Group
03 Nov LATAM Airlines Group
04 Nov LATAM Airlines Group
16 Nov LATAM Airlines Group
14 Nov LATAM Airlines Group
12 Nov LATAM Airlines Group
29 Nov LATAM Airlines Group
30 Nov LATAM Airlines Group
05 Nov LATAM Airlines Group

Also check the deals for return flights from Madrid to Santa Cruz in November.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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