Cheapest one-way flights from Madrid to Prague in September from 41€

AirHint found the following cheapest one-way flights from Madrid (MAD) to Prague (PRG) in September 2025 (see full year).

One-Way flights

24 Sep Ryanair direct
25 Sep Wizz Air Malta
16 Sep Ryanair direct
11 Sep Ryanair direct
17 Sep Ryanair direct
27 Sep Ryanair direct
18 Sep Ryanair direct
23 Sep Ryanair direct
13 Sep Ryanair direct
10 Sep Ryanair direct

Also check the deals for return flights from Madrid to Prague in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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