Cheapest one-way flights from Madrid to Prague in September from 38€

Best time to book flights for Madrid (MAD) to Prague (PRG) flights at AirHint

AirHint found the following cheapest one-way flights from Madrid (MAD) to Prague (PRG) in September 2025 (see full year).

One-Way flights

11 Sep Ryanair direct
04 Sep Ryanair direct
03 Sep Ryanair direct
10 Sep Ryanair direct
02 Sep Ryanair direct
06 Sep Ryanair direct
30 Sep Ryanair direct
26 Sep Wizz Air Malta
09 Sep ITA Airways
23 Sep ITA Airways

Also check the deals for return flights from Madrid to Prague in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Prague

Cheap car rent in Prague