Cheapest one-way flights from Madrid to Prague in September from 59€

Best time to book flights for Madrid (MAD) to Prague (PRG) flights at AirHint

AirHint found the following cheapest one-way flights from Madrid (MAD) to Prague (PRG) in September 2025 (see full year).

One-Way flights

12 Sep Wizz Air Malta
06 Sep Wizz Air Malta
04 Sep Wizz Air Malta
05 Sep Wizz Air Malta
09 Sep Ryanair direct
10 Sep Ryanair direct
06 Sep Ryanair direct
04 Sep Ryanair direct
25 Sep Ryanair
22 Sep Ryanair

Also check the deals for return flights from Madrid to Prague in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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